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Gallbladder Issues: Such as gallstones or cholecystitis
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The changes in fatty acid metabolism are thought to account for the improvement in hepatic insulin sensitivity and the decrease in serum triglyceride levels (48)

Novo Nordisk's semaglutide is produced at scale via a hybrid biological-chemical process 1 , while Eli Lillys tirzepatide is chemically synthesized 2

doi:10.1016/j.jacc.2021.12.012 Invokana (canagliflozin) [package insert]
3163 In Re: Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) Non-Arteritic Anterior Ischemic Optic Neuropathy Products Liability Litigation
