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Tirzepatide is the first combination of entero-pancreatic hormones [dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) RA] that has been approved for T2D management based on the findings from the phase 3 SURPASS programme

Patients with obesity and HFpEF typically have increased pulmonary vascular resistance and mean pulmonary artery pressure, as well as signs of right ventricular dysfunction

As employee interest in GLP-1 medications grows, employers may see more questions about insurance coverage, prior authorization, costs, and long-term use

Further research is needed to identify and manage possible side effects, such as the effects on gastric emptying and the need for safety precautions during anesthesia