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10.1016/j.neubiorev.2016.06.040 158 SchnellA.SandrelliF.RancV.RippergerJ

Allergies occur when your immune system mistakes harmless substances for harmful invaders

Studies have shown that the NOD-like receptor thermal protein domain associated protein 3 (NLRP 3) inflammasome, in response to cerebral ischemia, is activated through the pathogen-associated molecular pattern (PAMP)/DAMP signaling pathway, which promotes the conversion of caspase-1, thereby accelerating the process of pyroptosis in neuronal cells (46)