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Purity Collective does not provide dosing, clinical, therapeutic or administration instructions for this research product

Unlike some medications with circadian-dependent metabolism, B12 absorption mechanisms function consistently throughout the 24-hour cycle

Often described as tingling, prickling, or sunburn-like sensitivity

Pregnant and breastfeeding individuals need careful dosing, as B12 supports fetal nervous system development

Pairwise comparison of IGF-1 levels in the groups with different diagnoses using the Mann-Whitney U test revealed that IGF-1 levels significantly differed in the group BA and others ( = 0.004), BA, and Byler disease groups (0.012)