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The STEP and SURMOUNT trials consistently showed 26 to 40 percent of total weight lost was lean mass

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33 Sunitinib, another tyrosine kinase inhibitor, had a mean bioavailability with grapefruit consumption (200 mL, 3 times/d for 3 d) that was 111% of that compared with the level seen when grapefruit is not consumed

Excessive exposure to light and humidity can cause the breakdown of some medications, potentially altering their composition