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An online search utilizing the PubMed search engine was carried out using the MeSH terms Diabetes Mellitus, Hyperglycemia, Diabetes Complications, Hypoglycemic Agents, Glucagon-Like Peptide-1 Receptor Agonists, Glycoside Hydrolase Inhibitors, Acarbose, Metformin, Dipeptidyl-Peptidase IV Inhibitors, Sodium-Glucose Transporter 2 Inhibitors, Drug-Related Side Effects and Adverse Reactions, Gastrointestinal Diseases, Gastroparesis, Gastric Emptying, Dysbiosis, Gastrointestinal Microbiome, Microbiota, Constipation, Diarrhea, Nausea, Vomiting, Gastrointestinal Agents