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This strategy aligns with clinical guidelines suggesting that weight loss medications should be treated like chronic therapiessimilar to blood pressure or diabetes management

Our Palm Springs programs are structured specifically around muscle preservation for adults on semaglutide, tirzepatide, and other GLP-1 medications

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This research has been conducted using the UK Biobank Resource under Application Number 35327

Sensitivity tests Before PSM, the analysis of the crude populations showed consistent findings, indicating that GLP-1RA plus SGLT2i was associated with the primary composite outcome and individual outcomes compared to SGLT2i alone (Supplementary Table 4)