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They are like nonergot DAs in that they help with dyskinesia and motor fluctuations, but their use is limited due to cardiac side effects, including fibrosis and restrictive heart valve changes

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It is important to recall that tirzepatide for weight loss is not yet approved and this table assumes that the cost of tirzepatide for weight loss will be the same as the cost for diabetes though this may not be as in the case of semaglutide

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GLP-1 receptor agonists, including Ozempic, Wegovy, and Zepbound, have gained widespread attention as powerful tools for weight loss and appetite regulation

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2025;24 doi: 10.1186/s12933-024-02548-w

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