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In particular, the inhibition of ASK-1 ameliorated MASH and improved fibrosis in some patients in a short-term clinical trial
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Meissner W, Remy P, Giordana C, Maltete D, Derkinderen P, Houeto J, et al
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Thus, the autonomic nervous system, in particular the vagus nerve (which innervates a significant portion of the gut), is thought to play a role in this early phase of release, with nutrient content being more important for the second phase (85)
