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H., Change in Cardiometabolic Risk Factors Associated With Magnitude of Weight Regain 3 Years After a 1Year Intensive Lifestyle Intervention in Type 2 Diabetes Mellitus: The Look AHEAD Trial, Journal of the American Heart Association 8, no

This is where many providers pay closest attention to side effect tolerance

Shared decision-making to address the needs and preferences of each patient, and the individual characteristics that influence the risks and benefits of therapy for each patient are an important consideration [58]

Tong Q, Zheng L, Lin L, et al

This stands in sharp contrast to phentermine, where the appetite suppression is immediate and intense but fades as tolerance builds