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JAMA Psychiatry , was conducted by Ashok A

GLP-1 medications can produce substantial caloric restriction through appetite suppression and early satiety, leading to weight loss that may exceed 15-20% of body weight over several months with higher doses of semaglutide 2.4 mg or tirzepatide

Morgan Global Research, 29 Nov

Several research studies with rodents fed a high-fat diet, different animal models of obesity and diabetes, and patients diagnosed with T2DM have all shown changes in gut microbiota caused by metformin, as shown in Table 1

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