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Meal timing on GLP-1: many users find that one large meal causes more nausea than multiple small meals

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In 2020 the first small-molecule structure (Zhao et al) revealed a druggable transmembrane sub-pocket distinct from the peptide-binding interface

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Seek immediate medical attention if you experience large volumes of bright red blood, dizziness or fainting, severe abdominal pain, vomiting blood, black tarry stools, or signs of significant blood loss such as rapid heart rate or confusion