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PlexusDx's Precision Peptide Genetic Test ($99 add-on after your first month of treatment) analyzes 14 metabolic and appetite-regulation pathways, including your GLP1R and GIPR variants, to predict your genetic predisposition for GLP-1 response intensity

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Tirzepatide Tirzepatide is a GIPR and GLP-1R agonist that activates the body's receptors for GIP and GLP-1

For example, both medications can affect appetite, but in different ways, which could lead to unexpected results

In SUSTAIN-7, patients in the SEM 1 mg group had greater reduction in SBP and DBP than those with SEM 0.5 mg and DUL (Table 37)