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doi: 10.2337/diabetes.54.2.482 [DOI] [PubMed] [Google Scholar] 37
They are typically recommended for individuals with a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with obesity-related health conditions like high blood pressure or sleep apnea
Activities that once felt manageable suddenly feel draining
Semaglutide may also impact cortisol levels and stress response systems
The wide variability in deep compartment response is one reason the literature emphasizes superficial compartment loss as the more reliable signal
