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Topical anesthetic can be used to reduce pain, topical antiseptics can promote healing , and topical steroids can reduce inflammation

Most patients begin noticing changes within 2 to 4 weeks, with steady fat loss continuing over time

Weight Loss Plateau on Semaglutide Semaglutide (Wegovy) produces an average of 14.9% body weight loss at 68 weeks on the 2.4mg maximum dose, per the STEP 1 trial (Wilding et al., NEJM 2021)

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A 2022 clinical trial funded by Novo Nordisk (which makes Ozempic and Wegovy) found that a weekly dose of one GLP-1 drug reduced heavy-drinking days and total intake for people struggling with alcohol use disorder but only in a subgroup of patients with a BMI over 30