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Description
Reflux, Bloating, and Indigestion Retatrutide can affect digestion and fullness
During the titration phase, the dosage is increased by 2.5 mg increments every 4 weeks
Lancet Diabetes Endocrinol (2021) 9(10):65362
This makes sense mathematically but also reflects the greater metabolic adaptation present at higher weights
Clinical trials have demonstrated hemoglobin A1c reductions of 1.9% to 2.4% in type 2 diabetes (SURPASS trials), and weight loss of approximately 15% to 21% after 72 weeks in patients with obesity (SURMOUNT-1)
