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A four-week hold is roughly the window needed for a step to reach steady state and for the gut to adapt to it, which is why escalating before the block is complete effectively means judging a dose you have not yet fully experienced

adults have reportedly used a GLP-1 already, while 14% expressed interest

Secondary outcomes included endoscopy use and prescriptions for gastrointestinal medications such as laxatives and prokinetics

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By activating both GLP-1 and GIP receptors, tirzepatide offers a broader metabolic impact
