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Glucagon-like peptide-1 (GLP-1) agonists are the latest evolution of drugs that are reshaping the way we treat diabetes, obesity, and other forms of addiction.
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Upon reaching the brain compartment, substantial amounts of [Ser8]GLP-1 entered the brain parenchyma, but a large proportion was loosely associated with the vasculature at the BBB
GLP-1 RAs have been linked to bowel obstruction, particularly in those with prior GI motility problems
