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During arousal and orgasm, compounds are released that can affect male biology: - Copulins:fatty acids in vaginal secretions, often described aspheromone-like compounds, that may act as chemosignals influencing male hormonal responses and sexual motivation - Lactobacilli:a healthy vaginal microbiome supports microbial balance and may also contribute to overall urogenital health 3

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In the six-month INFUSE study, two infusions of eptinezumab reduced monthly headache days and increased good days in adults who had previously tried at least one CGRP preventive treatment