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There were no statistically significant interactions by treatment and background medication subgroup for change in HbA1c or body weight except for change in HbA1c (background insulin vs insulin plus metformin) in PIONEER 8 (p=0.0408)

When fiber reaches the colon, beneficial gut bacteria ferment it into short-chain fatty acids (SCFAs), which stimulate the release of GLP-1

Understanding your individual response risk factors and working with a healthcare provider to adjust dosing ensures safer, more effective outcomes
