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We also publish: the 2025 Summary of Major Modifications and Explanatory Notes as compared to the 2024 List

In the United States, obesity-attributable healthcare spending reaches USD 260 billion annually

Those three fill-finish plants already produced GLP-1 drugs (with ~3,000 employees) and will now be dedicated to Novos pipeline, alleviating the bottleneck
Around one in three adults with diagnosed diabetes using insulin also incorporates GLP-1 therapy, reflecting strong physician adoption and integration into standard care

The exception is that Zepbound is FDA-approved to treat excess weight and obesity and Mounjaro is FDA-approved to treat type 2 diabetes
