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Water retention increases temporarily, often in response to hormonal shifts or changes in sodium intake

10.1002/smll.202408581 Small 46 QianZ.ChenH.XiaM.ChangJ.LiX.YeS.et al (2022)

has almost doubled since 1998, as illustrated in the following graph

This may be related to sympathetic activation by DPP4 inhibition (Packer, 2018)