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Some patients and providers may hesitate to advance to higher doses due to side effects, but remaining at lower doses often results in suboptimal weight loss

What was the first symptom you noticed

doi: 10.3349/ymj.2000.41.1.68

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Dorsomedial hypothalamus GLP-1R are known to be expressed in the neurons of the DMH of mice and humans, and previous studies have emphasized its role in regulating metabolic responses by exendin-4 [68,69]