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In addition, in the majority of countries where its use for weight control has been approved, for it to be prescribed, the patient must have actual health problems related to his or her weight

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renal function should be monitored if significant vomiting or diarrhoea occurs Contraindications include pregnancy, while breastfeeding is not recommended

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The effect of hyperglucagonemia on resting metabolic rate (RMR) has been studied in subjects by indirect calorimetry, indicating that there was a significant increase in RMR during glucagon infusion [25]

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