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Description
Both prevent sharp increases in blood sugar, but while metformin reduces absorption of glucose in the small intestine, insulin removes glucose once it enters the blood

Exenatide and lixisenatide are synthetic peptides that fully resemble the sequence of exendin-4, a GLP-1 paralog that is naturally found in the saliva of the gila monster ( heloderma suspectum )
Woodard GA, Downey J, Hernandez-Boussard T, Morton JM

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