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Description
clinical trials, case reports, observational studies, or FAERS analyses describing oral or salivary adverse effects associated with GLP-1 receptor agonists
Apparently, GLP-1 has a protective effect on the LPS-induced RAW264.7 cell
The EM structure of Tirzepatide bound to the complete GLP-1R and G-proteins (Figure 2, PDB ID 7rgp , Sun et al., 2022) shows some hydrophobic and some specific polar interactions between the peptidic drug and the GLP-1 receptor molecule
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