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Data from the World Health Organization (WHO) shows that obesity has almost tripled globally since 1975, impacting over 650 million adults and 340 million children and adolescents in 2016

It was unexpectedly observed that plasma levels for the drug were significantly elevated compared to individuals without PWS, potentially explaining the high number of dropouts

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This has resulted in these two types of drugs being actively recommended as first-line agents in patients with diabetes with established atherosclerotic cardiovascular disease (ASCVD) [1]

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