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Most patients report noticing changes within the opening week, though the intensity and duration vary based on individual metabolism, genetics, and starting dose
Similarly, semaglutide ameliorates doxorubicin-induced cardiotoxicity by reducing BNIP3-mediated mitochondrial dysfunction through the PI3K/AKT pathway, enhancing mitochondrial function and reducing cardiac injury (Li et al., 2024), potentiating its clinical application in cardiovascular diseases

Effect of GLP-1 on the gut microbiota is involved in the inflammatory response Disturbance of the gut microbiota can promote endotoxemia and insulin resistance

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