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This medium was then replaced with 200 L RPMI 1640 supplemented with 2.2 mM or 16.8 mM glucose and Exendin-4-Fc (1 nM, 10 nM, or 100 nM) for 2 h

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Two hitherto approved oral peptide drugs, Rybelsus and Mycapssa , have been successfully converted to oral dosage forms using the PE strategy, and research is underway for the development of oral dosage forms of many peptide drugs through a similar strategy

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