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Inhibitors of DPP-4 showed only minimal pharmacokinetic changes in patients with varying degrees of hepatic impairment.70 Among agonists of GLP-1 receptors, only liraglutide has been studied in patients with CLD.72 No increase in liver enzymes was observed with this drug alone or combined with other agents

It is believed that by inhibiting the sweet taste sensation, people taking it will limit their intake of sweet foods, and this activity may be partially responsible for its hypoglycemic effect [14]

[DOI] [PMC free article] [PubMed] [Google Scholar] 198.Lin S, Faust L, Robles-Granda P, Kajdanowicz T, Chawla NV

(34) Given the increased risk of sarcopenia, osteoporosis, and frailty in older adults, future research should explore the long-term effects of GLP-1 receptor agonists on musculoskeletal health in this population, alongside their established systemic benefits
