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These medications work by mimicking the action of GLP-1, thereby helping to regulate blood sugar levels and reduce appetite

Therefore, therapeutic options that could work in a way other than classic antidepressants are being sought to increase the effectiveness of the treatment

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Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can reduce CV risk in patients with T2D, and both are recommended by the American Diabetes Association to reduce the risk of major cardiovascular events (MACE)