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Description
The diabetes version follows a similar pattern: If manufacturing an oral version requires complex formulations, intensive dosing schedules, and strains the supply chain by demanding more API for the same therapeutic effect, why bother developing it

There is no perfect number

In 1980 the World Health Organization (WHO) distinguished diabetes as being either insulin-dependent, or noninsulin-dependent ( Ewald and Bretzel ( Figure 1 )

had shown that injecting the short version of GLP-1 into rats profoundly reduced food intake

Yabut JM, Drucker DJ
