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The mechanism of protraction relates to slowed release from the injection site, and a reduced elimination rate owing to metabolic stabilisation and reduced renal filtration

Nauck and the other, anonymous reviewer(s) for their contribution to the peer review of this work

Eating less than you need to maintain your weight forces your body to call upon stored fat reserves to make up the difference

The 7th day was the rest day when mice had free access to normal water for 2 h

Drinking lots of water and eating small meals throughout the day also makes you feel better