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Gastroenterology 2011;141:150156 [DOI] [PMC free article] [PubMed] [Google Scholar] 4.Butler PC, Matveyenko AV, Dry S, Bhushan A, Elashoff R

Hemodynamic effect of a single dose of glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide in patients with diabetic kidney disease

Forsmark, C

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Nonetheless, research focusing on their safety during pregnancy is scarce, with existing studies primarily addressing metabolic effects rather than gestational safety.224 Given that GLP-1/GIP dual agonists modulate multiple metabolic pathways, further research is necessary to elucidate their potential impact on fetal development.227 Additionally, safety assessments of GLP-1RAs and GLP-1/GIP dual agonists in non-pregnant women have identified common adverse reactions, including gastrointestinal discomfort and anorexia