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Variations in the GLP1R gene (such as rs6923761), the GIPR gene (rs1800437), and metabolic regulators like FTO (rs9939609) and MC4R (rs17782313) influence individual sensitivity to semaglutide and the likelihood of hitting a plateau

Patients should be instructed to seek immediate medical attention for red-flag symptoms including intractable vomiting, severe dehydration, acute abdominal pain, gastrointestinal bleeding, or recurrent hypoglycemia, which may indicate surgical complications requiring urgent evaluation by the bariatric surgery team

Ozempic is typically self-injected once per week subcutaneously (under the skin of the stomach, abdomen, thigh, or upper arm)

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In addition, having low levels of sodium, potassium, magnesium, and calcium can contribute to muscle cramps, stiffness, and joint pain