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Increasing incidence of early-onset colorectal cancer

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The effects of GLP-1RAs on thyroid cancer risk Multiple retrospective observational studies and spontaneous case reports suggest a possible association between GLP-1RAs and an elevated risk of thyroid cancer [20, 21]
For context, in a previous Phase 3 trial of Zepbound, the highest-dose group saw a dropout rate of only 6.2% due to adverse events

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