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The risk of cardiovascular disease increases by three to six-fold with the coexistence of diabetes and hypertension

The idea is to use the lowest dose possible to achieve the desired results while minimizing the risk of any adverse side effects

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To improve the chances of successful surgery and of eliminating any cancer cells that may have already escaped from the tumor, patients are given cisplatin-based chemotherapy for a period before surgery, known as neoadjuvant therapy, or after surgery, known as adjuvant therapy
