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Clinical trial data reveals that nausea, diarrhoea, vomiting, constipation, and abdominal pain affect a substantial proportion of patients, particularly during dose escalation

Most troubling for individuals with diabetes, the erratic changes in blood sugar caused by gastroparesis can make diabetes worse, creating a feedback loop that worsens the gastroparesis

This was predominantly driven by the continuing roll-out of Novo Nordisks semaglutide and Lillys tirzepatide, and off-label use of their respective T2D-indicated brands

The Question of Long-Term Use Because GLP-1 medications are relatively new, scientists are still studying their long-term metabolic effects

"That's why I've been able to stay on it for as long as I have," VanGilder said