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However, it should be recalled that most results obtained so far derive from preclinical studies, and in vivo investigations in humans are thus necessary to fill this gap

To examine whether the chemical conjugation of MK-801 to GLP-1 mitigates the adverse hyperthermic and hyperlocomotive effects of MK-801, mice were subjected to body temperature measurements and open-field behavioural tests after chronic and acute drug administration, respectively

Compounded medications represent a distinct category
