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Escalate semaglutide slowlyby 0.25 mg weekly every 34 weeksuntil you reach an effective dose that matches your weight loss goals without intolerable side effects

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If a reduction in SBP of 1 mmHg is expected for every 1 kg of weight loss, the STEP trial cohorts might expect a SBP reduction of the magnitude of 13 mmHg, rather than the 5 mmHg observed

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