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Address GI symptoms early: Do not power through severe vomiting or diarrhea

Step-down within Wegovy: If side effects appear at 2.4 mg, your provider may lower the dose to 1.7 mg

While GLP-1 drugs can result in 15-25% total body weight loss, surgery often achieves 25-35% or more, with higher rates of long-term maintenance and remission of related diseases

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Huang L., Feng T

Beneficial effects were seen consistently across measured cardiovascular endpoints with semaglutide 2.4 mg