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McDougle, M., de Araujo, A., Singh, A., Yang, M., Braga, I., Paille, V., Mendez-Hernandez, R., Vergara, M., Woodie, L

2023 May 1;72(5):599-610

Specifically, neuropeptide Y/agouti-related protein (NPY/AgRP) neurons control appetite by the orexigenic effect47), and pro-opiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) neurons are sensitive to peripheral hormones such as insulin and leptin by anorexigenic effects48)

The product information itself tells prescribers: In case of significant gastrointestinal symptoms, consider delaying dose escalation or lowering to the previous dose until symptoms have improved. 1 That is a prescribers decision and not something to do on your own

Novo Nordisk is unique in that the vast majority of their revenue is concentrated in the category of metabolic health
