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Description
EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis

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The classification of diabetes can be done in two types as: Type-1 (insulin-dependent diabetes mellitus, IDDM) and Type-2 (non-insulin-dependent diabetes mellitus, NIDDM) [20, 21]

Concentration-dependent inhibition of forskolin-stimulated cAMP was observed for each GPR17 (IC 50 values ranging from 1.5-3.3 nM), with maximal inhibition observed in the 100-300 nM MDL29,951 range (Figure S3A and Table S1)

National Academy of Medicine
