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The remaining literature examining plasma and serum DHEA(S) concentrations in depression is inconsistent, with the decreased DHEA(S) findings described above, and with reports of either increased [117

Clinical trials show weight loss is often secondary to broader metabolic and cardiovascular benefits

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I suspect this is from the glucagon agonism of the drug as glucagon stimulates the formation of extra bile acids/bile salts in the liver which can be very irritating to the intestinal lining causing diarrhea

These could be signs of a serious condition