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However, these medications can also cause gastrointestinal side effects such as oily stools and flatulence

CHAKRABARTI: So Professor Holst, I wanted to ask you about this because there do seem to be the spectrum of intensity of side effects for these GLP-1 seems to be quite large, and the more and more people who come on it or who go on it and with staying on it for a longer period of time, are you concerned that we may start seeing side effects that are so severe that it would cast some doubt on the efficacy of GLP-1s

"This is why we felt it was important to make Ozempic, the GLP-1 with the broadest range of FDA-approved indications for adults with type 2 diabetes, more affordable to those without insurance who deserve the real thing." Ozempic is the GLP-1 with the most FDA-approved uses for patients with type 2 diabetes including, improvement of blood sugar, along with diet and exercise, in adults with type 2 diabetes, risk reduction of major cardiovascular events such as heart attack, stroke, or death in adults also with known cardiovascular (CV) disease, lowering the risk of worsening kidney disease, kidney failure (end-stage kidney disease), and death due to CV disease in adults who also have chronic kidney disease.1 Today, millions of people have taken Ozempic2 in the US to help address these chronic conditions, yet there are still some without adequate coverage seeking improved access.

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Histological analysis Pancreas were dissected and directly fixed in 4% paraformaldehyde overnight before embedding in paraplast (Paraplast X-tra, 39603002, Leica)