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On evidence, it is the weakest of the list for PCOS specifically, because it sits at zero PCOS trials while every other row has at least some direct data

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The concern extends beyond obvious culprits like soda
[DOI] [PMC free article] [PubMed] [Google Scholar] 169.Vasu S., Moffett R.C., Thorens B., Flatt P.R
Individuals with sluggish metabolism or suspected liver congestion
