semaglutide and hashimoto's disease Frontiers The multifaceted effects of semaglutide:

Liraglutide administration reversed diabetes-related LTP blockade and actively promoted LTP formation in DIO mice (157, 158), while rescuing hippocampal LTP loss in an ob/ob murine model of obesity-diabetes (164)

doi:10.1016/S0140-6736(14)60976-4 New Zealand Society for the Study of Diabetes

And Ozempics manufacturer, Novo Nordisk, got the ingredient semaglutide FDA approved as Wegovy in 2021

When semaglutide (the agonist) binds to the GLP-1R, the receptor changes shape

So this is an area where there is a need to develop new treatments. Mahavir Agarwal, a psychiatrist who coleads the Mental Health and Metabolism Clinic at the Centre for Addiction and Mental Health, says GLP-1 drugs are worth investigating if only for antipsychotic side effect management in people with psychiatric conditions