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Quick tip: When reading trial results, separate average weight change from personal expectations

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

Zepbound is indicated for adults with obesity or those who are overweight and also have weight-related medical problems, to lose weight and keep it off

It also slows gastric emptying, which prolongs the feeling of fullness and reduces food intake

In higher doses, Ozempic also acts on the brain to reduce appetite and generate feelings of fullness