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doi: 10.1371/journal.pone.0087466 Summary Keywords oral semaglutide, body composition, fat mass, visceral adipose tissue, fat free mass, skeletal muscle mass, type 2 diabetes, GLP-1RA Citation Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Lavarra V, Triggiani D, Crudele L, Triggiani V, Sabb C, De Pergola G and Piazzolla G (2023) Oral semaglutide improves body composition and preserves lean mass in patients with type 2 diabetes: a 26-week prospective real-life study

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For others, it could mean staying on the lowest dose of a GLP-1 medication instead of gradually increasing, deviating from what the clinical trials indicate is needed for weight loss and lower than the doses approved for weight maintenance by the FDA, says Nidhi Kansal, MD , an internal medicine specialist at Northwestern Medical Group