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However, a dose-dependent insulinotropic and glucagonostatic response is preserved in response to exogenous GLP-1 treatment and 6-week subcutaneous GLP-1 infusion was shown to improve HbA1c levels by 1.3% [18]

They are the "engine oil" of your biology

I'm gonna quote Alex Telford who wrote this really amazing, long blog post explaining how the clinical trial process works, why drug development has gotten so expensive, and all that

While most of our patients who try the injections feel great benefits from them, the following people are particularly likely to feel the positive effects of B12: vegans, vegetarians, patients whose primary source of protein is chicken, patients who have undergone gastric sleeve or gastric bypass surgery, and patients taking diabetes medication, acid reflux medication, or antibiotics

12 General healthy eating patterns, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension (DASH) diet, provide excellent frameworks, emphasizing vegetables, fruits, whole grains, lean protein, and healthy fats while limiting added sugars, refined grains, and unhealthy fats